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Article
December 1978

Familial ComedonesEvidence for Autosomal Dominant Inheritance

Author Affiliations

From the Divisions of Genetics and Hematology (Drs Cantú and Sánchez-Corona) and Experimental Pathology (Dr González-Mendoza), Subjefatura de Investigación Básica, Unidad de Investigación Biomédica, Centro Médico de Occidente, Instituto Mexicano del Seguro Social and from the Hospital Civil (Dr Gómez-Bustamente), Guadalajara, Jalisco, Mexico.

Arch Dermatol. 1978;114(12):1807-1809. doi:10.1001/archderm.1978.01640240049016
Abstract

• Thirteen members of a family had multiple comedones. Three other relatives were also ascertained to be affected. This peculiar dermatosis affected both sexes and was present in one individual as young as 10 years of age. The lesions were more numerous in male family members, increasing in number with age. The pedigree showed a definite pattern of autosomal dominant inheritance.

(Arch Dermatol 114:1807-1809, 1978)

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