Tuberous sclerosis is a dominantly inherited neurocutaneous syndrome characterized by epilepsy, mental retardation, and various types of fibrous hyperplasia including facial angiofibromas (adenoma sebaceum), brain fibromas (tubera), subungual fibromas, oral fibromas, skin tags, collagen nevi, phacomas, and various visceral and skeletal fibrous and muscular tumors. In addition, café au lait spots, white hypopigmented macules, poliosis, and tooth enamel pits may be associated.
The purpose of this report is to present a case of previously undiagnosed tuberous sclerosis in a 20-year-old that was unusual in that the patient had a giant angiofibroma and multiple skin tags.
Report of a Case
A 20-year-old man presented himself for the evaluation of an abscess in a "birthmark" on his face. Examination showed an irregular 6.5 × 5-cm brownish-red plaque on the left malar area that had numerous papules and nodules on its surface (Fig 1). A draining abscess was present in its lower
Willis WF, Garcia RL. Giant Angiofibroma in Tuberous Sclerosis. Arch Dermatol. 1978;114(12):1843-1844. doi:10.1001/archderm.1978.01640240073022