There is increasing evidence that, as in systemic lupus erythematosus (SLE), deposition of immune complexes plays a role in the pathogenesis of dermatitis herpetiformis (DH). Dermatitis herpetiformis and SLE were diagnosed in a 15-year-old girl with Marfan's syndrome who died of cardiac tamponade secondary to cystic medial necrosis of the ascending aorta. The concurrence of these diseases suggests that predisposition to immune-mediated disorders may be associated with the expression of multiple clinical entities.
(Arch Dermatol 115:68-70, 1979)
Aronson AJ, Soltani K, Aronson IK, Ong RT. Systemic Lupus Erythematosus and Dermatitis HerpetiformisConcurrence With Marfan's Syndrome. Arch Dermatol. 1979;115(1):68-70. doi:10.1001/archderm.1979.04010010040011