To the Editor.—
We read with interest the letter to the editor "Treatment of Psoriasis With Dialysis" by Dr Anderson in the June 1978 issue of the Archives (114:966), as well as the related article in the Annals of Internal Medicine. Our experience has been similar to his. Although some of our patients' conditions have remained clear for prolonged periods of time, the conditions of others have not responded.1,2 We have also noted rapid recurrence (six weeks) after dialysis therapy and the remission of psoriasis with associated arthritis after cardiopulmonary bypass oxygenation.3To the studies which Dr Anderson suggested, we would like to add the use of hemodialysis and monitors of the immune mechanisms involved. Since psoriasis is a disease of epidermal proliferation, dermal hypervascularization, early mononuclear infiltration, and, finally, late neutrophil invasion, it may well be that substances elaborated by these invading cells modulate the epidermal proliferation.
Buselmeier TJ, Cantieri JS. Dialysis and Psoriasis. Arch Dermatol. 1979;115(3):370. doi:10.1001/archderm.1979.04010030068033