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Article
May 1979

Epidermal Nevus With Cutaneous Endocrinal Associations

Author Affiliations

From the Faculty of Medicine, Alexandria, Egypt.

Arch Dermatol. 1979;115(5):625-626. doi:10.1001/archderm.1979.04010050055021
Abstract

In 1968, Solomon and his associates1 reported a high incidence of congenital skeletal and CNS abnormalities in patients with epidermal nevi. They proposed the term "epidermal nevus syndrome" for cases combining these features with cutaneous hemangiomas, multiple nevus cell nevi, cafeau-lait spots, and other pigmentary changes.

In a comprehensive review of these cases, Dimond and Amon2 stated that simultaneously occurring but unrelated tumors can develop in patients with epidermal nevi without any causal interrelationship.

We report an interesting case of a verrucose epidermal nevus with a pituitary tumor and other cutaneous endocrinal features.

Report of a Case  A 44-year-old man, married but with no children, sought medical advice for declining libido and sexual potency with persistent headache over the last eight years. Clinical examination revealed several cutaneous and systemic abnormalities, all present since shortly after birth. There was no family history of similar lesions.Cutaneous changes included an

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