To the Editor.—
Notowicz et al1 have reported the successful use of topical mechlorethamine hydrochloride in Hallopeau's acrodermatitis; according to Arnold,2 intramuscular administration of triamcinolone acetonide should always be tried in this disorder. These reports prompt me to suggest that ethylester retinoid should be given orally in Hallopeau's acrodermatitis.I saw, as a patient, a 55-year-old woman with an acropustulosis on a finger of her left hand, of 25 years' duration, without any associated skin disorder (Fig 1). After one week of treatment with a 0.075% solution of ethylester retinoid, there was a dramatic improvement.Three more weeks of treatment with a 0.05% concentration resulted in complete remission, with a normal finger and a growing nail plate (Fig 2). Additional patients are under study at the present time and will be reported on shortly.
Baran R. Hallopeau's Acrodermatitis. Arch Dermatol. 1979;115(7):815. doi:10.1001/archderm.1979.04010070001001