A lymphangiosarcoma arose at the site of a preexisting lymphangioma circumscriptum on the skin of the anterior part of the abdominal wall. To our knowledge, this is only the second such case to be reported, and in both patients, the preexisting lymphangioma circumscriptum had been exposed to substantial x-ray therapy. Since it is possible that x-irradiation may play a role in the development of this unusual malignant neoplasm, it seems advisable that lymphangioma circumscriptum not be exposed to substantial amounts of such radiation, if feasible.
(Arch Dermatol 115:969-972, 1979)
King DT, Duffy DM, Hirose FM, Gurevitch AW. Lymphangiosarcoma Arising From Lymphangioma Circumscriptum. Arch Dermatol. 1979;115(8):969-972. doi:10.1001/archderm.1979.04010080033018