An observed clinical side effect of total skin surface electron beam therapy is the patient's inability to perspire. An evaluation of eccrine sweat gland function was performed, utilizing acetylcholine chloride and a silicone impression material. The patient's inability to sweat after therapy, and recovery within a three-to six-month period after therapy was demonstrated. This phenomenon should be appreciated by both the physician and the patient prior to electron beam therapy in order to avoid the potential complications of this condition.
(Arch Dermatol 115:1068-1070, 1979)
Price NM. Electron Beam TherapyIts Effect on Eccrine Gland Function in Mycosis Fungoides Patients. Arch Dermatol. 1979;115(9):1068-1070. doi:10.1001/archderm.1979.04010090018015