In two black patients, squamous cell carcinoma of the lip developed within lesions of discoid lupus erythematosus (DLE). The association of DLE and squamous cell carcinoma is unusual in blacks, as is the anatomical site involved in these cases. Enhanced metastatic potential may be present when squamous cell carcinoma arises in DLE of the lips.
(Arch Dermatol 115:1214, 1979)
Martin S, Rosen T, Locker E. Metastatic Squamous Cell Carcinoma of the LipOccurrence in Blacks With Discoid Lupus Erythematosus. Arch Dermatol. 1979;115(10):1214. doi:10.1001/archderm.1979.04010100034014