Contact urticaria developed in a patient after topical application of paraben-containing compounds. Positive open patch test results and a positive passive transfer (Prausnitz-Küstner reaction) test demonstrated an immunologic mechanism for the patient's skin reaction. The importance of parabens to contact urticaria is described.
(Arch Dermatol 115:1231-1232, 1979)
Henry JC, Tschen EH, Becker LE. Contact Urticaria to Parabens. Arch Dermatol. 1979;115(10):1231-1232. doi:10.1001/archderm.1979.04010100051021