Papulonodular eruptions from certain bromide and iodide preparations are widely recognized entities, but skin lesions following fluoride ingestion are rare. Modern prophylaxis for postirradiation dental caries includes the use of fluoride gel preparations applied to the teeth. In two patients receiving such therapy a papulonodular eruption developed, similar to the recognized halogenodermas. These cases may help to increase awareness of this entity.
(Arch Dermatol 115:1334-1335, 1979)
Blasik LG, Spencer SK. Fluoroderma. Arch Dermatol. 1979;115(11):1334-1335. doi:10.1001/archderm.1979.04010110040022