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December 1979

Necrolytic Migratory Erythema Without GlucagonomaReport of Two Cases

Author Affiliations

From the Metabolism (Drs Goodenberger and Strober) and Dermatology (Drs Lawley and Katz) Branches, National Cancer Institute, National Institutes of Health, Bethesda, Md; Washington Memorial Hospital (Dr Wyatt), Turnerville, NJ; the Division of Gastroenterology, Waterbury Hospital (Dr Sangree), Waterbury, Conn; and the Departments of Medicine (Dr Sherwin) and Dermatology (Drs Rosenbaum and Braverman), Yale University School of Medicine, New Haven, Conn.

Arch Dermatol. 1979;115(12):1429-1432. doi:10.1001/archderm.1979.04010120027012

Two patients with clinical and histologic findings consistent with necrolytic migratory erythema are presented. Unlike previously described patients with this disorder, neither patient had substantially elevated glucagon levels nor an associated pancreatic islet cell tumor. The cause of the skin disease in these patients remains unknown but may be related to the underlying small-bowel disorder present in both.

(Arch Dermatol 115:1429-1432, 1979)