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January 1980

A Syndrome of Multiple Immune AutoreactivityA Breakdown in Immune Regulation

Author Affiliations

From the Departments of Dermatology (Drs Diaz and Glamb) and Internal Medicine (Dr Silva), University of Michigan Medical School, Ann Arbor.

Arch Dermatol. 1980;116(1):77-79. doi:10.1001/archderm.1980.01640250079022

• The clinical findings of pemphigus vulgaris, rheumatoid arthritis, and Sjögren's syndrome were found in a patient displaying immunological abnormalities found in pemphigus vulgaris, systemic lupus erythematosus, rheumatoid arthritis, and Hashimoto's thyroiditis. Some of the antigen-antibody systems detected in this case were further identified. Our patient may be an example of severe failure in immune regulation.

(Arch Dermatol 116:77-79, 1980)