Physicians should be on their guard for unusual presentations of syphilis.1 Before the advent of effective chemotherapy for the disease, physicians were familiar with a large number of morphologic variants, some of which are no longer well known. We present an example of one of these variants, corymbose secondary syphilis. Only a solitary lesion was present.
Report of a Case
A 27-year-old homosexual man had a three-month history of a symptomless patch over the right scapula. He was in excellent general health. Four and a half years earlier, the patient had come to a venereal disease clinic with an extensive maculopapular eruption. At that time, a VDRL test was reactive at a titer of 1:32, and Treponema pallidum hemagglutination (TPHA) and FTA tests were reactive.He had been treated with intramuscular injections of penicillin G procaine, but he defaulted after receiving eight daily doses of 1 megaunit per dose.
Kennedy CTC, Sanderson KV. Corymbose Secondary SyphilisOccurrence as a Solitary Group of Lesions. Arch Dermatol. 1980;116(1):111-112. doi:10.1001/archderm.1980.01640250113028