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This is an interesting and informative book that deserves to be read by most physicians. The paraneoplastic phenomena refer to various indirect and usually remote effects produced by metabolites or other products of tumor cells. Coverage of the subject is broad. The book is partly based on Dr Waldenström's own experiences and, as such, lets us share in the large body of medical information that propelled the successful career of this outstanding clinician-investigator.
The book is divided into two parts. The first, "Signals From Organ Systems Indicating the Presence of Neoplasia," consists of six chapters about the skin, the nervous system, blood, the skeleton and ossification, the vascular system, and the kidney. The second, "General Signals and Specific Substances Indicating Neoplasia," consists of five chapters entitled "General Symptoms and Immunological Markers," "Specific Tumor-Produced Biochemical Disorders," "Disorders of Derepressed Immunoglobulin Synthesis," "Neoplasias Producing Specific Substances," and "Ectopic Production of Hormonally Active
Muller SA. Paraneoplasia: Biological Signals in the Diagnosis of Cancer. Arch Dermatol. 1980;116(1):121. doi:10.1001/archderm.1980.01640250123036