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March 1980

The Correlation of Disease Activity and Antibody Titers in Pemphigus

Author Affiliations

From the Division of Dermatology, University of California Center for the Health Sciences, Los Angeles.

Arch Dermatol. 1980;116(3):285-290. doi:10.1001/archderm.1980.01640270045011

• Twenty cases of pemphigus extracted from the literature and 19 patients from UCLA with pemphigus were studied in detail regarding the possible correlation of pemphigus titer and disease activity. A statistically significant relationship between titer and disease activity, as well as change in titer and change in disease activity, was found. However, in spite of this relationship, serial titers were not found to be consistent enough to be used reliably as a guide to therapy or prognosis in pemphigus.

(Arch Dermatol 116:285-290, 1980)