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April 1980

Cutaneous Plasmacytoma?

Author Affiliations

Orange, Calif

Arch Dermatol. 1980;116(4):381. doi:10.1001/archderm.1980.01640280017002

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To the Editor.—  We read with interest the fascinating article by Canlas et al (Archives 115:722-724, 1979) in which the authors described what they believed to be the 11th reported case of primary cutaneous plasmacytoma. However, we were concerned about the criteria for this diagnosis. The only evidence the authors presented supporting the interpretation of a plasmacytoma was a single photomicrograph. This photomicrograph exhibited a poorly differentiated neoplasm consisting of "plasmacytoid" cells arranged in an alveolar pattern. Many tumors show these histologic features including malignant melanoma, renal cell carcinoma, and germ cell neoplasms. All of these may also contain a reactive plasma cell infiltrate. Although the cutaneous plasmacytoma is a rare lesion, there are several additional features that raise questions regarding the validity of the authors' diagnosis but do not necessarily exclude it. These include highly anaplastic and bizarre cytologic features, a rapid downhill course with death occurring within

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