To the Editor.—
In the June Archives (115:678,1979), Nielsen reported a case of basal cell epithelioma arising in a BCG vaccination scar. He stated that he was unaware of any such cases reported previously. Recently, we observed a 31-year-old patient with basal cell nevus syndrome who showed basal cell epitheliomas following needle punctures.1 One basal cell epithelioma, measuring 5 cm, developed 18 years after a BCG vaccination on the upper part of the right arm. The other tumor, measuring 3 mm, appeared three years after an intravenous drip on the back of the left hand. Reviewing the literature, we found a description of basal cell carcinoma following BCG vaccination by Ben-Hur et al in 1963.2 These authors described two patients with basal cell epitheliomas that developed 1½ and 12½ years after BCG vaccination.
Panizzon R. Basal Cell Epithelioma in a BCG Vaccination Scar. Arch Dermatol. 1980;116(4):381-382. doi:10.1001/archderm.1980.01640280017004