† Lymphocytes from psoriatic patients were found to contain reduced levels of adenosine 3′:5′-cyclic phosphate, guanosine 5′-cyclic phosphoric acid, and prostaglandin E, as compared with lymphocytes from normal subjects. The difference in prostaglandin F levels between psoriatic and control subjects was not statistically significant. These results could point to an immunologic defect in the immune system in psoriasis.
(Arch Dermatol 116:427-428, 1980)
Harpaz S, Fink A, Zuckerman F, Muhammad E. Lymphocyte Cyclic Nucleotide and Prostaglandin Content in Psoriasis: A Preliminary Report. Arch Dermatol. 1980;116(4):427-428. doi:10.1001/archderm.1980.01640280063020