• Hypersensitivity, manifested by generalized nummular eczematous and papular dermatitis, and presumably by contact urticaria, developed in a 47-year-old man after four years of using oral and topical aloe. Patch tests for aloe were positive in this patient.
(Arch Dermatol 116:1064-1065, 1980)
Morrow DM, Rapaport MJ, Strick RA. Hypersensitivity to Aloe. Arch Dermatol. 1980;116(9):1064-1065. doi:10.1001/archderm.1980.01640330102026