[Skip to Content]
[Skip to Content Landing]
Article
November 1980

Lack of Delayed Reaction in Presence of Cell-Mediated Immunity in Trichophytin Hypersensitivity

Author Affiliations

From the Department of Dermatology, University of Geneva.

Arch Dermatol. 1980;116(11):1266-1268. doi:10.1001/archderm.1980.01640350056014
Abstract

• Five patients with atopy who had chronic dermatophytosis manifested an immediate and strong trichophytin skin reaction but no delayed reaction. This phenomenon may be caused by the neutralization of injected antigen by serum antibodies during the immediate reaction. When we injected a second dose of trichophytin into the wheal of the immediate reaction, 20 minutes after the first injection, a strong delayed reaction was elicited, demonstrating cell-mediated immune responses in these patients.

(Arch Dermatol 116:1266-1268, 1980)

×