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January 1981

Multiple Clear Cell Acanthoma

Author Affiliations

Limoges Cedex, France

Arch Dermatol. 1981;117(1):1. doi:10.1001/archderm.1981.01650010005002

To the Editor.—  We read with interest the article by Trau et al in the Archives (1980;116;433-434) about a new case of multiple clear cell acanthoma. We have observed a similar case with unusual locations and regressive evolution.

Report of a Case.—  A man born in 1927 was initially seen in our dermatology department in February 1979 with multiple tumors of five years' duration. More than 50 lesions were noted, mainly on the legs, but a few were observed on the anterior part of the chest, one on the dorsum of the right wrist, and one about 2 cm in diameter in the perianal region. The tumors were either squamous or showed a smooth surface. The tumor in the perianal region and four others from the legs were removed. Microscopic examination showed the changes in all five lesions. The ultrastructural study mainly showed keratinocytes filled with glycogen, as previously described.

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