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January 1981

Familial Variant of Dermatofibroma With Malignancy in the Proband

Author Affiliations

From the Departments of Pathology (Dr Roberts) and Medicine (Drs Byrne and Rosenthal), McMaster University and Henderson General Hospital, Hamilton, Ontario.

Arch Dermatol. 1981;117(1):12-15. doi:10.1001/archderm.1981.01650010018015

• Multiple fibrous histiocytomas of the dermis (dermatofibromas) were found in six males of one family. A number of the tumors fell within the histologic patterns commonly encountered in dermatofibromas, but some were unusually large and others were cytologically atypical. In addition, the proband died of a malignant fibrous histiocytoma of the lung. We believe that this is a syndrome and a familial variant of a common dermal entity.

(Arch Dermatol 117:12-15, 1981)