Winkelmann and Su1 recently described a female patient who had vegetating lesions resembling pemphigus vegetans. The histopathologic and immunologic findings, however, were typical for bullous pemphigoid. The authors, therefore, termed this unique presentation of bullous pemphigoid, "pemphigoid vegetans."
This report describes a patient with similar clinical and immunohistologic findings. She also had roentgenologically confirmed ulcerative colitis.
Report of a Case
A 40-year-old woman was first seen by us 12 years ago, soon after the onset of a purulent, vegetating dermatitis involving her hands, eyelids, lips, axillae, vulva, and groin. Four years earlier she had had erythema nodosum, the cause of which remained unknown, although she had had colitis for many years.A clinical diagnosis of pemphigus vegetans was made, although acantholysis could not be found on histopathologic examination. The patient was subsequently hospitalized several times because of relapsing lesions, which often occurred in association with respiratory or urinary tract
Kuokkanen K, Helin H. Pemphigoid VegetansReport of a Case. Arch Dermatol. 1981;117(1):56-57. doi:10.1001/archderm.1981.01650010062029