† A photodermatitis developed in two patients after the use of commercial sunscreens and a topical anesthetic lotion containing benzocaine. Photopatch testing indicated the presence of photocontact allergy to benzocaine. One patient had a positive photopatch test to a commercial glyceryl para-aminobenzoic acid (PABA) preparation that was heavily contaminated with benzocaine, but not to a benzocaine-free sample of glyceryl PABA. Benzocaine failed to produce phototoxic reactions in normal volunteers. Efforts to induce photocontact allergy in guinea pigs were unsuccessful.
(Arch Dermatol 117:77-79, 1981)
Kaidbey KH, Allen H. Photocontact Allergy to Benzocaine. Arch Dermatol. 1981;117(2):77-79. doi:10.1001/archderm.1981.01650020019016