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May 1981

Pretibial Myxedema

Author Affiliations

Springfield, Ill

Arch Dermatol. 1981;117(5):250-251. doi:10.1001/archderm.1981.01650050004004

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To the Editor.—  In a recent report in the September Archives (1980;116:1076-1077), Kucer et al described the recurrence of pretibial myxedema within the graft sites of a patient with hyperthyroidism. We have had a similar experience with a patient with hypothyroidism.

Report of a Case.—  A 47-year-old woman was first seen at another institution in 1965. At that time, her complaints were exophthalmos and skin nodules on the middle of the dorsum of her left foot. Thyroid function test results showed her to have hypothyroidism. A test result for long-acting thyroid stimulator was positive. Thyroid replacement therapy was initiated.In 1972, bilateral orbital decompression was required for her severe exophthalmos. In 1975, each of the two nodules on the dorsum of her left foot had grown to 2 cm in diameter. The lesions were asymptomatic, flesh colored, and waxy in consistency, with prominent hair follicles. Biopsy specimens (hematoxylin-eosin stained) of

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