Cutaneous amebiasis is uncommon in the United States. Its recognition is important since it may be confused with a variety of infectious and neoplastic lesions.
Report of a Case
A 58-year-old woman was seen in the Dermatology Clinic at the University of California, Irvine, with a one-month history of a bloody pruritic eruption of the perianal region. Six weeks previously she had been examined in the Gynecology Clinic for a follow-up evaluation of a vaginal hysterectomy; no anal or perianal lesions were noted at that time.Physical examination revealed an odoriferous 3 × 3-cm exudative, verrucous plaque with a necrotic center in the gluteal cleft at the superior border of the anus (Fig 1). The differential diagnosis included condyloma acuminatum, condyloma latum, verrucous carcinoma, pemphigus vegetans, and cutaneous amebiasis. Routine laboratory study results were within normal limits. A urine culture showed no growth and a VDRL test result was negative.
Fujita WH, Barr RJ, Gottschalk HR. Cutaneous Amebiasis. Arch Dermatol. 1981;117(5):309-310. doi:10.1001/archderm.1981.01650050065026