[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.197.90.95. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
July 1981

Disseminated Spiked HyperkeratosisAn Unusual Discrete Nonfollicular Keratinization Disorder

Author Affiliations

From the Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

Arch Dermatol. 1981;117(7):412-414. doi:10.1001/archderm.1981.01650070040021
Abstract

• An unusual nonfollicular keratinization disorder was observed in a father and his son, and in an unrelated woman. The disorder began during the second decade of life and gradually became more widespread and more pronounced thereafter. The dermatosis is characterized by tiny, rough, keratotic spikes giving the skin a raspy feel on palpation. Microscopically, the lesions showed a thick compact stratum corneum without structural changes in the underlying epidermis except for moderate epidermal cell hyperplasia and some reduction in keratohyalin content.

(Arch Dermatol 1981;117:412-414)

×