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August 1981

The Use of Technetium Tc 99m Medronate Scintigraphy as a Prognostic Guide in Childhood Dermatomyositis

Author Affiliations

Bordeaux, France

Arch Dermatol. 1981;117(8):451. doi:10.1001/archderm.1981.01650080003002

To the Editor.—  Dermatomyositis remains a severe disease problem, despite therapy. In childhood, muscle and fascial calcinosis may appear after two or more years1 and generally occurs after an acute flare of the disease. It is frequently associated with a favorable outcome.Conventional roentgenograms do not disclose all of the calcium deposits in this disease complication and do not give maximum information on the evolution and course of the calcinosis, which remains uncertain and is functionally disabling.We observed a 12-year-old boy who had been treated with 2 mg/kg/day of prednisone for four years for dermatomyositis. Laboratory investigation results were almost normal, in contrast with his painful functional disability. We carried out technetium Tc 99m medronate scintigraphy to find out if the calcification made visible by roentgenography2 was progressive or not. The radiopharmaceutical uptake increases when the local calcification processus becomes aggravated. Thus, this technique only stains "hot"

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