To the Editor.—
The short report of Sarma in the February 1980 Archives (116:226-227) entitled "Angiosarcoma of the Nose" is a most interesting one. However, I find it disturbing that, in his references to this article, Sarma did not refer to the fact that angiosarcoma of the liver has been associated with exposure to vinyl chloride.1,2 For this patient, there was no report of an occupational history. However, the patient does come from an area that has an extensive petrochemical industry. In addition, I think it is important to be aware of these associations and to make note of articles concerning them that have appeared in the general medical literature. It should be noted that angiosarcoma of the liver has been associated with arsenic exposure and the use of thorium dioxide. There was no history given concerning possible exposure to these agents.
Rubin DF. Occupational History and Angiosarcoma. Arch Dermatol. 1981;117(8):452-453. doi:10.1001/archderm.1981.01650080004005