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Dr Flach seems to be asking two questions: (1) Did I do a biopsy on all the molluscum papules, thereby curing them through some local irritation or immune process? No, because there were about 50 molluscum papules. Biopsies were done on five. The remainder disappeared without being traumatized and without biopsies being done. (2) Could a systemic immune response, resulting in the disappearance of all the papules, have occurred after a few of the papules were traumatized when biopsies were done? No, because many molluscum papules became inflamed and disappeared before the first biopsy.
Steffen C. Spontaneous Disappearance of Molluscum Contagiosum or New Approach to Treatment?-Reply. Arch Dermatol. 1981;117(9):527-528. doi:10.1001/archderm.1981.01650090007010