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October 1981

An Unusual Transformation of a Common Wart in a Child

Author Affiliations

Bordeaux, France


Arch Dermatol. 1981;117(10):607. doi:10.1001/archderm.1981.01650100007012

To the Editor.—  We read with special interest the article by Lutzner et al in the January Archives (1981;117:43-46) about a curious type of wart in a renal allograft recipient. We recently observed a boy with a peculiar tendency for common warts. One of them persisted for five years and, microscopically, had a surprising pseudoepitheliomatous appearance.

Report of a Case.—  An 11-year-old boy, with no substantial previous medical history, had a verrucous lesion of five years' duration on his right buttock. For the past year, this lesion had appeared to be thicker, and additional lesions had appeared on the extremities, eyelids, and knees.A biopsy specimen from the buttock lesion showed microscopic changes on epidermal acanthosis with pseudoepitheliomatous hyperplasia and a chronic inflammatory cell infiltrate in the dermis. Features of viral cytopathogenic effect, eg, vacuolation, were rare. We did not detect papilloma viral antigens with immunoperoxidase staining.

Comment.—  This lesion

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