• Three patients in three generations of a Puerto Rican family had lichen amyloidosis. The HLA typing in nine family members suggested a possible relationship to the HLA-B locus antigen known as 4c. The 4c antigen (a complex of cross-reacting antigens) or one of its components has been associated with multiple myeloma and Hodgkin's disease. HLA associations with other amyloid-related illnesses are discussed.
(Arch Dermatol 1981;117:639-642)
De Pietro WP. Primary Familial Cutaneous AmyloidosisA Study of HLA Antigens in a Puerto Rican Family. Arch Dermatol. 1981;117(10):639-642. doi:10.1001/archderm.1981.01650100041025