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November 1981

Cutaneous Malignant Mixed Tumor

Author Affiliations

From the Departments of Pathology and Dermatology, Dermatopathology Unit, Massachusetts General Hospital, Harvard Medical School, Boston (Drs Harrist, Aretz, and Mihm); Department of Surgical Pathology, Winchester (Mass) Hospital (Dr Evans); and Department of Pathology, Quincy City (Mass) Hospital (Dr Rodriquez).

Arch Dermatol. 1981;117(11):719-724. doi:10.1001/archderm.1981.01650110041016

• Two cases of cutaneous malignant mixed tumor occurred in a 70-year-old man and a 69-year-old man. Nine previously described patients with cutaneous malignant mixed tumor resembled the two patients in this report, both clinically and histologically. All cases with adequate long-term follow-up evaluations were characterized by recurrence or metastasis. In contrast to benign mixed tumors, these tumors tend to occur on the extremities, are of larger size, and may exhibit rapid growth. Histologically, cellular atypism, increased cellularity, increased mitotic rate, invasion of surrounding tissue, and necrosis may be identified.

(Arch Dermatol 1981;117:719-724)