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November 1981

Dermal Mucinosis in Discoid Lupus ErythematosusReport of Two Cases

Author Affiliations

From the Dermatology Service, Veterans Administration Medical Center, and the Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City (Drs Weigand and Burgdorf); and the Department of Medicine, University of Oklahoma Tulsa Medical College (Dr Gregg).

Arch Dermatol. 1981;117(11):735-738. doi:10.1001/archderm.1981.01650110057022

• Two patients with discoid lupus erythematosus (DLE) had lesions exhibiting prominent atrophy and telangiectasia. At the time of biopsy, the skin specimens were grossly mucinous. Light and immunofluorescence microscopy findings confirmed the diagnosis of DLE in both cases. Abundant mucin deposition throughout the dermis was also seen microscopically in both cases. Although secondary mucinosis is known to occur in LE, cases with massive mucinous change, ie, those reported herein, have apparently not been recorded. Mucinosis is not considered important in the histologic diagnosis of LE but may create some confusion with other mucinous disorders.

(Arch Dermatol 1981;117:735-738)