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December 1981

Generalized Dermal Melanocytosis

Author Affiliations

From the Departments of Pathology (Drs Bashiti and Blair), Pediatrics (Dr Triska), and Dermatology (Dr Keller), Cardinal Glennon Memorial Hospital for Children, St Louis. Dr Bashiti is now with the St Louis University Hospitals.

Arch Dermatol. 1981;117(12):791-793. doi:10.1001/archderm.1981.01650120037018

• A female infant was born with generalized blue-gray discoloration of the skin. Light microscopy demonstrated the diffuse distribution of dihydroxyphenylalanine-positive, dermal melanocytes. Electron microscopy confirmed the identification of the pigment-bearing cells as melanocytes and demonstrated individual melanocytes to be invested with a filamentous extracellular sheath. To our knowledge, comparable, generalized, dermal melanocytosis has not previously been reported in a newborn.

(Arch Dermatol 1981;117:791-793)