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Article
February 1982

Pulse TherapyTherapeutic Efficacy in the Treatment of Pyoderma Gangrenosum

Author Affiliations

From the Department of Medicine, Division of Dermatology, Duke University Medical Center, Durham, NC.

Arch Dermatol. 1982;118(2):76-84. doi:10.1001/archderm.1982.01650140008008
Abstract

• Three patients with pyoderma gangrenosum were treated with suprapharmacologic doses of methylprednisolone sodium succinate using a five-day pulse therapy regimen. This therapy produced a dramatic remission with minimal side effects. The effects of pulse therapy are reviewed, and its role in severe steroid-responsive dermatoses is discussed.

(Arch Dermatol 1982;118:76-84)

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