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April 1982

The Ectodermal Dysplasias-Reply

Arch Dermatol. 1982;118(4):216. doi:10.1001/archderm.1982.01650160005007

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In Reply.—  We thank Drs Pinheiro and Freire-Maia for their comments. We are, of course, familiar with Dr Freire-Maia's views but must regretfully decline to agree on a number of points. We believe the term "anhidrotic," as applied to the CST syndrome, to be appropriate. Indeed, one may find a drop of sweat here and there, but, functionally and histologically, our patients with this syndrome are essentially devoid of sweat glands.Except for their pointing out some typographical errors and one mistake (the tooth and nail syndrome is an autosomal dominant condition), the rest of their letter concerns itself with a statement of disagreement. We respect their view but again decline to agree with many points, a perfect example of which is their last point. What they consider to be an ED—alopecia, vitiligo, and nail changes—may not be a hereditary condition. They take from the literature that with which they

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