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Article
May 1982

Treatment of Keratoacanthoma With Topical Application of Fluorouracil

Author Affiliations

USA; USA; USA; USA; USA

From the Dermatology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco.

Arch Dermatol. 1982;118(5):309-311. doi:10.1001/archderm.1982.01650170023015
Abstract

• Keratoacanthomas (KAs) in 14 patients were treated with 20% fluorouracil ointment, two or three times daily, for two to four weeks. All lesions responded promptly and cleared in an average period of 3.4 weeks (range, one to seven weeks). Allergic contact dermatitis to fluorouracil occurred in two patients. This treatment response suggests that topical application of fluorouracil ointment is an effective alternative to conventional methods of treating KA.

(Arch Dermatol 1982;118:309-311)

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