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Article
May 1982

Familial Vulvar Dystrophy of Lichen Sclerosus Type

Author Affiliations

From the Departments of Medicine (Dermatology) (Drs Murphy and Haberman) and Pathology (Dr Lipa), Toronto Western Hospital and the University of Toronto. Dr Haberman is an associate of the Ontario Cancer Treatment and Research Foundation.

Arch Dermatol. 1982;118(5):329-331. doi:10.1001/archderm.1982.01650170043021
Abstract

• Lichen sclerosus et atrophicus (LS&A) of the vulva and perianal skin is an atrophic condition that can occur alone or in association with additional lesions situated elsewhere on the skin surface. The cases of three sisters with LS&A of the vulva are reported herein; in one a squamous cell carcinoma developed in a hyperplastic area of mixed dystrophy (LS&A with fociof hyperplasia). Familial occurrences of LS&A are rare. Malignant neoplasms arising in areas of LS&A have been reported previously. Squamous cell carcinoma arises in hyperplastic areas of mixed dystrophy where there is evidence of both LS&A and epithelial hyperplasia.

(Arch Dermatol 1982;118:329-331)

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