• An 84-year-old man was examined for progressive pain, edema, and infiltrating skin lesions on his lower extremities. A skin biopsy specimen confirmed the suspected diagnosis of angioendotheliomatosis proliferans. The clinical course and histologic changes suggested the malignant form of this disease. Treatment with intravenous doxorubicin hydrochloride caused a complete clinical remission.
(Arch Dermatol 1982;118:512-514)
Keahey TM, Guerry D, Tuthill RJ, Bondi EE. Malignant Angioendotheliomatosis Proliferans Treated With Doxorubicin. Arch Dermatol. 1982;118(7):512-514. doi:10.1001/archderm.1982.01650190066022