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Article
November 1982

Primary Localized Gigantism and Tuberous Sclerosis

Author Affiliations

Nice, France

Lyons, France

Arch Dermatol. 1982;118(11):877-878. doi:10.1001/archderm.1982.01650230005008
Abstract

To the Editor.—  Primary local gigantism remains a rare clinical entity that occurs either spontaneously or, more often, in association with neurofibromatosis.1 We saw a patient in whom this type of abnormality was associated with tuberous sclerosis.

Report of a Case.—  A 30-year-old man was noted during infancy to have had gigantism of the upper part of his left limb that slowly progressed throughout life. His medical history disclosed that the patient had had convulsions during childhood Family history disclosed that a son of the propositus had tuberous sclerosis with convulsions and white macules on the skin.Findings from a physical examination showed diffuse enlargement of the upper part of the left arm, thumb, and index finger. The circumference of the upper part of the left arm was greater than that of the right arm, although there was no difference in the length. The skin looked normal; there was

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