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November 1982

Nodular Superficial Pigmented Basal Cell EpitheliomasLong-term Fluorouracil Treatment

Author Affiliations

From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia. Dr Shelley is now with the University of Illinois College of Medicine, Peoria School of Medicine.

Arch Dermatol. 1982;118(11):928-930. doi:10.1001/archderm.1982.01650230056029

† Eradication of multiple nodules, papules, and plaques of pigmented basal cell epitheliomas of the back of one patient was achieved by nine months of daily treatment with 5% fluorouracil cream. Such topical chemotherapy offers the physician an alternative to surgery and radiation in treating patients who have widespread nodular superficial epitheliomas. The need for a prolonged period of treatment and follow-up is emphasized.

(Arch Dermatol 1982;118:928-930)