• Two adult patients with skin lesions typical of histiocytosis X were treated topically with mechlorethamine hydrochloride. In the patient whose disease was limited to the skin, a sustained remission was induced, but in the patient with extensive systemic disease, cutaneous remission lasted only six weeks.
(Arch Dermatol 1983;119:157-161)
Nethercott JR, Murray AH, Medwidsky W, Chalvardjian A. Histiocytosis X in Two AdultsTreatment With Topical Mechlorethamine. Arch Dermatol. 1983;119(2):157-161. doi:10.1001/archderm.1983.01650260065021