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Article
March 1983

PRECANCEROUS DERMATOSES: A STUDY OF TWO CASES OF CHRONIC ATYPICAL EPITHELIAL PROLIFERATION

Arch Dermatol. 1983;119(3):243-260. doi:10.1001/archderm.1983.01650270061020
Abstract

THE various cutaneous conditions that may precede the development of cancer have been sometimes grouped, more or less loosely, under the title "Precancerous Conditions," "Precancerous Keratoses," etc. Thus, Dubreuilh1 in his paper "Des hyperkératoses circonscrites," read at the International Congress of Dermatology in London, 1896, discusses under the heading "precancerous keratoses," the following affections: cornu cutaneum, keratoma senile, xeroderma pigmentosum, arsenical cancer, chimneysweep's cancer, cancer in workers in paraffine and tar, and leucokeratoses. Keratosis follicularis (Darier's disease) and Paget's disease, are cited as affections which, although not strictly coming under the head of keratoses, have a distinct analogy with the precancerous keratoses.

Hartzell1, in a paper read at a meeting of the American Dermatological Association in Washington in 1903, touches upon various affections of the skin such as tuberculosis, syphilis and various benign new growths, that may be followed by cancer, together with the forms of keratoses just mentioned.

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