[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.204.247.205. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
April 1983

Multiple Clear Cell Acanthomas

Author Affiliations

USA; USA

From the Dermatology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco.

Arch Dermatol. 1983;119(4):359-361. doi:10.1001/archderm.1983.01650280087024
Abstract

In 1962, Degos et al1 described an uncommon benign skin tumor, histologically identifiable by sharply demarcated, regular acanthosis. They named it clear cell acanthoma. Under microscopic examination, the tumor was found to consist of pale epidermal cells containing abundant amounts of glycogen, as evidenced by PAS-positive and diastase labile stains. Further clinical and histologic characterization followed publication of this report.2,3

The acanthoma arises as an asymptomatic, single, erythematous papule or plaque, measuring 5 to 10 mm in diameter. It occurs in both sexes, usually in midlife. It most commonly appears on the lower part of the leg, especially on the calf. A fine, scaly layer may cover the tumor, which blanches on diascopy and bleeds easily with minor trauma, mimicking a pyogenic granuloma.

The solitary clear cell acanthoma is an uncommon tumor. Multiple lesions, however, are truly rare, with only 12 cases reported to date. We report herein

First Page Preview View Large
First page PDF preview
First page PDF preview
×