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Article
August 1983

Leukapheresis for the Treatment of Psoriasis

Author Affiliations

Department of Haematology Royal Hobart Hospital Hobart, Tasmania, Australia

Arch Dermatol. 1983;119(8):629-630. doi:10.1001/archderm.1983.01650320003004
Abstract

To the Editor.—  In recent years, there have been some articles in the literature concerning the treatment of psoriasis by a variety of extracorporeal devices, namely, hemodialysis,1 peritoneal dialysis,2 cardiopulmonary bypass oxygenation,3 and plasmapheresis.4 We describe a similar method of treatment—leukapheresis. Like the other methods, our initial experience was an incidental finding of an unexpected response in a volunteer donor, a man aged 34 years, with psoriasis who was undergoing leukapheresis to provide granulocytes for a relative. His psoriasis, which had been troublesome for more than 20 years, almost disappeared for five months before it gradually returned.

Report of a Case.—  After explaining the procedure and obtaining informed consent, we electively treated a 29-year-old man who had widespread psoriasis, who had been previously treated with the most common modes of treatment, including methotrexate therapy and steroids given for systemic effect. Apart from the extent of the

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