• The carcinogenic effect of artificial UV sunlight followed by UV-A irradiation in human solaria doses has been studied with the use of the hairless mouse as an animal model. Artificial sunlight exposure alone induced only a moderate skin tumor incidence (animals with at least one tumor) of 0.15 after one year, and UV-A irradiation alone induced no tumor formation. However, the combination of artificial sunlight exposure and subsequent UV-A irradiation significantly increased the tumor incidence to 0.72. We conclude that, in humans, tanning with UV-A for cosmetic purposes may not be an innocuous procedure.
(Arch Dermatol 1983;119:641-643)
Staberg B, Wulf HC, Poulsen T, Klemp P, Brodthagen H. Carcinogenic Effect of Sequential Artificial Sunlight and UV-A Irradiation in Hairless MiceConsequences for Solarium `Therapy'. Arch Dermatol. 1983;119(8):641-643. doi:10.1001/archderm.1983.01650320015008