To the Editor.—
Pilomatrixoma is a tumor usually located in the dermis and composed of sharply demarcated, round cellular islands, producing a lobulated contour. Of the more than 1,500 cases reported in the literature, approximately 96% of the patients had solitary lesions. After reviewing the available literature, Moehlenbeck1 deduced that the incidence of multiple pilomatrixoma was 3.5%. However, there were no cases of histopathologically established multicentric pilomatrixoma contained in one clinical lesion.
Report of a Case.—
A healthy 27-year-old man had a tender and slightly pruritic lump on the upper lateral aspect of his left arm develop in 1974. The lesion ulcerated spontaneously and was treated with acriflavine-soaked gauze by his physician. Two years later, when the patient was first seen by us at the dermatology, clinic, a firm nodule that was erythematous peripherally and eroded centrally, developed on the upper lateral aspect of his left arm. The tumor
Shoji A, Hamada T. Histologic Variation of a Pilomatrixoma. Arch Dermatol. 1983;119(10):793-794. doi:10.1001/archderm.1983.01650340003008