Sympathectomy, as a surgical treatment for angina pectoris, was first reported by Jonnesco1 in Bucharest, Rumania, in 1920. The operation consisted of denervation of cervical sympathetic chains and both of the first dorsal root ganglia, resulting in pronounced relief for the patient from his chest pain. Following this apparent success, many surgical variations were introduced, each created with the purpose of relieving angina pectoris by cardiac denervation. These procedures were associated with a 10% to 20% operative mortality, and approximately 80% of patients achieved relief from pain.
Beck et al2 initiated the next phase of coronary artery study. Their attempts were directed at increasing or redistributing the coronary blood flow. The idea for this approach came from their observation that bleeding occurred after the division of pericardial adhesions. They substantiated this discovery with animal experiments in which artificially induced pericarditis resulted in organized vasculature that supplied blood from
Najafi H. Update on Surgical Management of Coronary Artery Disease. Arch Dermatol. 1983;119(11):930-933. doi:10.1001/archderm.1983.01650350058018